{"id":150021,"date":"2025-07-31T15:42:03","date_gmt":"2025-07-31T14:42:03","guid":{"rendered":"https:\/\/www.exseedhealth.com\/?p=150021"},"modified":"2025-11-12T14:08:30","modified_gmt":"2025-11-12T14:08:30","slug":"autoimmune-diseases-in-men-how-they-impact-male-fertility","status":"publish","type":"post","link":"https:\/\/www.exseedhealth.com\/sv\/autoimmune-diseases-in-men-how-they-impact-male-fertility\/","title":{"rendered":"Autoimmuna sjukdomar hos m\u00e4n: Hur de p\u00e5verkar manlig fertilitet"},"content":{"rendered":"<p>Autoimmuna sjukdomar drabbar miljontals m\u00e4nniskor runt om i v\u00e4rlden, och vissa av dem upptr\u00e4der oftare eller allvarligare hos m\u00e4n. Dessa tillst\u00e5nd orsakar vanligtvis inflammation och organproblem, men de p\u00e5verkar ocks\u00e5 fertiliteten - en bieffekt som ofta f\u00f6rbises. Nedan g\u00e5r vi igenom fem autoimmuna sjukdomar som \u00e4r vanligare hos m\u00e4n och f\u00f6rklarar hur var och en av dem kan skada den reproduktiva h\u00e4lsan.<\/p>\n<h2>Ankyloserande spondylit (AS)<\/h2>\n<p><strong>Vad det \u00e4r:<\/strong><br \/>\nAnkyloserande spondylit \u00e4r en typ av inflammatorisk artrit som fr\u00e4mst drabbar ryggraden och lederna i nedre delen av ryggen. Den b\u00f6rjar ofta i tidig vuxen \u00e5lder och f\u00f6rekommer ungef\u00e4r tv\u00e5 till tre g\u00e5nger oftare hos m\u00e4n (<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Braun%20J%2C%20Sieper%20J.%20Ankylosing%20spondylitis.%20Lancet.%202007%20Apr%2021%3B369%289570%29%3A1379%E2%80%9390.\" target=\"_blank\" rel=\"noopener noreferrer\">Braun &amp; Sieper, 2007<\/a>).<\/p>\n<p><strong>P\u00e5verkan p\u00e5 fertiliteten:<\/strong><\/p>\n<ul>\n<li>Kronisk inflammation \u00f6kar den oxidativa stressen, vilket kan skada spermiernas form, r\u00f6relse och DNA (<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Ricci%20G%2C%20et%20al.%20Semen%20quality%20in%20young%20men%20with%20ankylosing%20spondylitis%20treated%20with%20NSAIDs%20or%20TNF-%CE%B1%20inhibitors.%20Fertil%20Steril.%202009.\" target=\"_blank\" rel=\"noopener noreferrer\">Ricci m.fl. 2009<\/a>).<\/li>\n<li>Inflammatoriska hormoner kan s\u00e4nka testosteronet och f\u00f6rs\u00e4mra spermieproduktionen.<\/li>\n<li>Sm\u00e4rta, stelhet och tr\u00f6tthet leder ofta till erektionsproblem och minskad libido.<\/li>\n<li>L\u00e4kemedel som kallas TNF-h\u00e4mmare (t.ex. etanercept eller adalimumab) verkar s\u00e4kra f\u00f6r fertiliteten och kan till och med f\u00f6rb\u00e4ttra spermiernas h\u00e4lsa (<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Mahmoud%20AM%2C%20et%20al.%20Effects%20of%20etanercept%20on%20male%20fertility%20in%20patients%20with%20AS.%20Rheumatol%20Int.%202011.\" target=\"_blank\" rel=\"noopener noreferrer\">Mahmoud m.fl. 2011<\/a>).<\/li>\n<\/ul>\n<h2>Psoriasis och psoriasisartrit (PsA)<\/h2>\n<p><strong>Vad det \u00e4r:<\/strong><br \/>\nPsoriasis \u00e4r en l\u00e5ngvarig hudsjukdom som orsakar r\u00f6da, fj\u00e4llande fl\u00e4ckar. Cirka 30% av alla personer med psoriasis utvecklar ocks\u00e5 psoriasisartrit, som orsakar ledv\u00e4rk och svullnad. Dessa tillst\u00e5nd tenderar att upptr\u00e4da tidigare och utvecklas snabbare hos m\u00e4n.<\/p>\n<p><strong>P\u00e5verkan p\u00e5 fertiliteten:<\/strong><\/p>\n<ul>\n<li>Inflammation \u00f6kar den oxidativa stressen i sperman, vilket kan minska spermiernas antal och r\u00f6relse.<\/li>\n<li>Synliga hudsymtom och sm\u00e4rta kan p\u00e5verka sj\u00e4lvf\u00f6rtroendet och leda till att man undviker sex.<\/li>\n<li>Inflammatoriska kemikalier som TNF-alfa och IL-17 kan st\u00f6ra hormonbalansen och minska testosteronet.<\/li>\n<li>Behandlingar som blockerar dessa cytokiner, t.ex. TNF- eller IL-17-h\u00e4mmare, \u00e4r i allm\u00e4nhet s\u00e4kra f\u00f6r m\u00e4n som vill ha barn (<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Micu%20MC%2C%20et%20al.%20Effects%20of%20IL-17%20and%20TNF%20inhibitors%20on%20male%20reproductive%20function.%20Reprod%20Biol%20Endocrinol.%202023.\" target=\"_blank\" rel=\"noopener noreferrer\">Micu et al, 2023<\/a>).<\/li>\n<\/ul>\n<h2>Reumatoid artrit (RA)<\/h2>\n<p><strong>Vad det \u00e4r:<\/strong><br \/>\nReumatoid artrit \u00e4r en autoimmun sjukdom som fr\u00e4mst angriper lederna men som ocks\u00e5 kan drabba hela kroppen. \u00c4ven om det \u00e4r vanligare hos kvinnor, upplever m\u00e4n ofta en mer aggressiv form av sjukdomen.<\/p>\n<p><strong>P\u00e5verkan p\u00e5 fertiliteten:<\/strong><\/p>\n<ul>\n<li>M\u00e4n med RA har ofta l\u00e4gre testosteronniv\u00e5er och h\u00f6gre LH-niv\u00e5er, ett tecken p\u00e5 hormonell obalans (<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Kiss%20E%2C%20et%20al.%20Hormonal%20disturbances%20in%20men%20with%20rheumatoid%20arthritis.%20Clin%20Rheumatol.%202005.\" target=\"_blank\" rel=\"noopener noreferrer\">Kiss m.fl. 2005<\/a>).<\/li>\n<li>P\u00e5g\u00e5ende inflammation kan skada spermiernas DNA och f\u00f6rs\u00e4mra deras kvalitet.<\/li>\n<li>Depression, tr\u00f6tthet och ledv\u00e4rk kan s\u00e4nka libido och p\u00e5verka den sexuella f\u00f6rm\u00e5gan.<\/li>\n<li>Vanliga RA-l\u00e4kemedel, inklusive metotrexat och biologiska l\u00e4kemedel, skadar vanligtvis inte fertiliteten, men l\u00e4kare rekommenderar ibland att man tar en kort paus innan man f\u00f6rs\u00f6ker bli gravid.<\/li>\n<\/ul>\n<h2>Diabetes mellitus typ 1 (T1DM)<\/h2>\n<p><strong>Vad det \u00e4r:<\/strong><br \/>\nTyp 1-diabetes \u00e4r ett autoimmunt tillst\u00e5nd som f\u00f6rst\u00f6r de insulinproducerande cellerna i bukspottk\u00f6rteln. Den b\u00f6rjar vanligtvis i barndomen eller ton\u00e5ren och kr\u00e4ver daglig insulinbehandling.<\/p>\n<p><strong>P\u00e5verkan p\u00e5 fertiliteten:<\/strong><\/p>\n<ul>\n<li>H\u00f6gt blodsocker \u00f6kar den oxidativa stressen och skadar sm\u00e5 blodk\u00e4rl, vilket kan skada spermiernas DNA och minska r\u00f6rligheten (<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Agbaje%20IM%2C%20et%20al.%20Increased%20sperm%20DNA%20damage%20in%20diabetic%20men.%20Reprod%20Biomed%20Online.%202007.\" target=\"_blank\" rel=\"noopener noreferrer\">Agbaje m.fl. 2007<\/a>).<\/li>\n<li>Nervskador kan orsaka erektil dysfunktion eller retrograd ejakulation.<\/li>\n<li>D\u00e5lig glukoskontroll kan rubba hormonerna och s\u00e4nka testosteronniv\u00e5n.<\/li>\n<li>Insulinbehandling i sig skadar inte fertiliteten, men om blodsockret h\u00e5lls stabilt skyddas den reproduktiva h\u00e4lsan.<\/li>\n<\/ul>\n<h2>Prim\u00e4r skleroserande kolangit (PSC)<\/h2>\n<p><strong>Vad det \u00e4r:<\/strong><br \/>\nPSC \u00e4r en kronisk leversjukdom som orsakar inflammation och \u00e4rrbildning i gallg\u00e5ngarna. Den drabbar m\u00e4n oftare \u00e4n kvinnor och upptr\u00e4der ofta tillsammans med ulcer\u00f6s kolit, en inflammatorisk tarmsjukdom.<\/p>\n<p><strong>P\u00e5verkan p\u00e5 fertiliteten:<\/strong><\/p>\n<ul>\n<li>Leverproblem kan st\u00f6ra hormonbalansen och s\u00e4nka testosteronniv\u00e5n och sexlusten.<\/li>\n<li>Konstant tr\u00f6tthet kan orsaka sexuella sv\u00e5righeter och minska motivationen.<\/li>\n<li>\u00c4ven om uppgifterna \u00e4r begr\u00e4nsade bidrar inflammation sannolikt till oxidativ skada p\u00e5 spermierna.<\/li>\n<li>L\u00e4kemedel som ursodeoxicholsyra (UDCA) och TNF-blockerare som anv\u00e4nds f\u00f6r IBD verkar i allm\u00e4nhet s\u00e4kra f\u00f6r manlig fertilitet.<\/li>\n<\/ul>\n<h2>Slutsats<\/h2>\n<p>Autoimmuna sjukdomar inneb\u00e4r m\u00e5nga utmaningar f\u00f6r m\u00e4n - inte bara sm\u00e4rta och tr\u00f6tthet utan ocks\u00e5 potentiella effekter p\u00e5 fertiliteten. Inflammation, oxidativ stress och hormonella f\u00f6r\u00e4ndringar kan alla skada spermierna och p\u00e5verka den sexuella h\u00e4lsan. Det finns dock goda nyheter: de flesta moderna behandlingar, s\u00e4rskilt biologiska l\u00e4kemedel, verkar vara s\u00e4kra f\u00f6r den manliga reproduktionsfunktionen.<\/p>\n<p><strong>M\u00e4n som lever med autoimmuna sjukdomar kan anv\u00e4nda <a href=\"https:\/\/shop.exseedhealth.com\/collections\/male-fertility-test-kits\" target=\"_blank\" rel=\"noopener noreferrer\">Testkit f\u00f6r spermier i hemmet<\/a> f\u00f6r att f\u00f6lja fertilitetsh\u00e4lsan<\/strong> - inklusive spermiernas antal, form och r\u00f6rlighet. Testning f\u00f6re eller under behandlingen hj\u00e4lper m\u00e4n att fatta s\u00e4kra beslut och att arbeta n\u00e4rmare sina l\u00e4kare.<\/p>\n<p>Genom att hantera sjukdomsaktiviteten i ett tidigt skede och regelbundet kontrollera fertiliteten kan m\u00e4n skydda sin reproduktiva h\u00e4lsa och planera f\u00f6r framtida f\u00f6r\u00e4ldraskap med tillf\u00f6rsikt.<\/p>","protected":false},"excerpt":{"rendered":"<p>Autoimmune diseases affect millions of people around the world, and some of them appear more often or more severely in men. These conditions usually cause inflammation and organ problems, but they also affect fertility \u2014 a side effect that\u2019s often overlooked. Below, we explore five autoimmune diseases that are more common in men and explain [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":150025,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"content-type":"","footnotes":""},"categories":[200,198],"tags":[],"class_list":["post-150021","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-lifestyle-environmental","category-mens-fertility"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v28.2 (Yoast SEO v28.7) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>How Autoimmune Diseases Affect Male Fertility<\/title>\n<meta name=\"description\" content=\"Discover how autoimmune diseases impact male fertility, plus how at-home sperm testing can help men monitor reproductive health.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.exseedhealth.com\/sv\/autoimmune-diseases-in-men-how-they-impact-male-fertility\/\" \/>\n<meta property=\"og:locale\" content=\"sv_SE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"How Autoimmune Diseases Affect Male Fertility\" \/>\n<meta property=\"og:description\" content=\"Discover how autoimmune diseases impact male fertility, plus how at-home sperm testing can help men monitor reproductive health.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.exseedhealth.com\/sv\/autoimmune-diseases-in-men-how-they-impact-male-fertility\/\" \/>\n<meta property=\"og:site_name\" content=\"ExSeed Health\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/ExSeedHealth\" \/>\n<meta property=\"article:published_time\" content=\"2025-07-31T14:42:03+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2025-11-12T14:08:30+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.exseedhealth.com\/wp-content\/uploads\/2025\/07\/Visualizing-the-Impact-of-Autoimmune-Disease-1024x576.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1024\" \/>\n\t<meta property=\"og:image:height\" content=\"576\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"Emil Andersen, PhD\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@ExSeed_Health\" \/>\n<meta name=\"twitter:site\" content=\"@ExSeed_Health\" \/>\n<meta name=\"twitter:label1\" content=\"Skriven av\" \/>\n\t<meta name=\"twitter:data1\" content=\"Emil Andersen, PhD\" \/>\n\t<meta name=\"twitter:label2\" content=\"Ber\u00e4knad l\u00e4stid\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minuter\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.exseedhealth.com\\\/autoimmune-diseases-in-men-how-they-impact-male-fertility\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.exseedhealth.com\\\/autoimmune-diseases-in-men-how-they-impact-male-fertility\\\/\"},\"author\":{\"name\":\"Emil Andersen, PhD\",\"@id\":\"https:\\\/\\\/www.exseedhealth.com\\\/#\\\/schema\\\/person\\\/5d08eb43d90734a01dcf3cb77ce5e109\"},\"headline\":\"Autoimmune Diseases in Men: How They Impact Male Fertility\",\"datePublished\":\"2025-07-31T14:42:03+00:00\",\"dateModified\":\"2025-11-12T14:08:30+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.exseedhealth.com\\\/autoimmune-diseases-in-men-how-they-impact-male-fertility\\\/\"},\"wordCount\":690,\"publisher\":{\"@id\":\"https:\\\/\\\/www.exseedhealth.com\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/www.exseedhealth.com\\\/autoimmune-diseases-in-men-how-they-impact-male-fertility\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.exseedhealth.com\\\/wp-content\\\/uploads\\\/2025\\\/07\\\/Visualizing-the-Impact-of-Autoimmune-Disease.png\",\"articleSection\":[\"Lifestyle &amp; 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