{"id":120937,"date":"2023-10-21T10:55:36","date_gmt":"2023-10-21T09:55:36","guid":{"rendered":"https:\/\/www.exseedhealth.com\/?p=120937"},"modified":"2024-03-20T16:06:31","modified_gmt":"2024-03-20T16:06:31","slug":"mens-biological-clock","status":"publish","type":"post","link":"https:\/\/www.exseedhealth.com\/pl\/mens-biological-clock\/","title":{"rendered":"Czy m\u0119\u017cczy\u017ani maj\u0105 zegary biologiczne? M\u0119ska p\u0142odno\u015b\u0107 a wiek"},"content":{"rendered":"

Kiedy my\u015blimy o wp\u0142ywie wieku na p\u0142odno\u015b\u0107, nasze umys\u0142y cz\u0119sto koncentruj\u0105 si\u0119 na kobietach, skupiaj\u0105c si\u0119 na zmniejszaj\u0105cej si\u0119 poda\u017cy kom\u00f3rek jajowych, kwestiach chromosomalnych i niep\u0142odno\u015bci. Jedno z bada\u0144 wykaza\u0142o nawet, \u017ce 1 na 5 m\u0119\u017cczyzn uwa\u017ca niep\u0142odno\u015b\u0107 za problem wy\u0142\u0105cznie kobiet. Jest jednak co\u015b, o czym nie m\u00f3wi si\u0119 tak cz\u0119sto - wp\u0142yw wieku na m\u0119sk\u0105 p\u0142odno\u015b\u0107. Czy kiedykolwiek zalecano m\u0119\u017cczyznom zwracanie wi\u0119kszej uwagi na ich zegary biologiczne?<\/p>\n

 <\/p>\n

Czynnik wieku: Op\u00f3\u017anianie ojcostwa<\/h2>\n

Co zaskakuj\u0105ce, w wielu krajach nie zniech\u0119ca si\u0119 starszych m\u0119\u017cczyzn chc\u0105cych zosta\u0107 ojcami, w przeciwie\u0144stwie do sposobu, w jaki starszym kobietom cz\u0119sto odradza si\u0119 macierzy\u0144stwo. Na przyk\u0142ad Narodowy Instytut Doskona\u0142o\u015bci Klinicznej w Anglii i Walii, odradza NHS oferowanie zap\u0142odnienia in vitro kobietom powy\u017cej 42. roku \u017cycia<\/a>ale nie ma takiej wzmianki o wieku ojca w wytycznych. Kwestia tego, co jest uwa\u017cane za \"stare\" w kontek\u015bcie ojcostwa, pozostaje w du\u017cej mierze nierozwi\u0105zana.<\/p>\n

Niemniej jednak badania wskazuj\u0105, \u017ce oko\u0142o 40. roku \u017cycia sperma m\u0119\u017cczyzn zaczyna zwalnia\u0107, przez co pocz\u0119cie staje si\u0119 trudniejsze. Co wi\u0119cej, dzieci urodzone przez starszych ojc\u00f3w s\u0105 nara\u017cone na zwi\u0119kszone ryzyko wyst\u0105pienia chor\u00f3b takich jak autyzm, schizofrenia i bia\u0142aczka.<\/p>\n

W Stanach Zjednoczonych ro\u015bnie tendencja do tego, by m\u0119\u017cczy\u017ani zostawali ojcami w starszym wieku. W 1980 roku oko\u0142o 43 na 1000 dzieci urodzi\u0142o si\u0119 m\u0119\u017cczyznom w wieku 35-49 lat. Do 2015 r. liczba ta wzros\u0142a wzros\u0142a do oko\u0142o 69 na 1000 dzieci<\/a>.<\/p>\n

 <\/p>\n

Dlaczego jako\u015b\u0107 nasienia ma znaczenie: Wp\u0142yw wieku<\/h2>\n

Wiek ojca r\u00f3wnie\u017c wp\u0142ywa na jako\u015b\u0107 spermy. Systematyczny przegl\u0105d z 2015 roku, w kt\u00f3rym przeanalizowano 90 bada\u0144 z udzia\u0142em 93 839 os\u00f3b, wykaza\u0142, \u017ce wiek m\u0119\u017cczyzny negatywnie wp\u0142ywa na jako\u015b\u0107 nasienia, w tym wygl\u0105d, ruchliwo\u015b\u0107 i uszkodzenia DNA.<\/p>\n

Jako\u015b\u0107 nasienia odgrywa kluczow\u0105 rol\u0119 w pocz\u0119ciu dziecka. W badaniu z udzia\u0142em 2112 par z Wielkiej Brytanii stwierdzono, \u017ce m\u0119\u017cczy\u017ani w wieku powy\u017cej 45 lat prawie pi\u0119ciokrotnie cz\u0119\u015bciej potrzebowali ponad roku na pocz\u0119cie dziecka w por\u00f3wnaniu z m\u0119\u017cczyznami w wieku poni\u017cej 25 lat, nawet je\u015bli partnerka by\u0142a m\u0142oda.<\/p>\n

 <\/p>\n

Ryzyko zwi\u0105zane z p\u00f3\u017aniejszym posiadaniem dzieci<\/h2>\n

Wyniki zap\u0142odnienia in vitro (IVF) dla starszych m\u0119\u017cczyzn r\u00f3wnie\u017c wydaj\u0105 si\u0119 by\u0107 mniej korzystne. Niedawne badanie obejmuj\u0105ce 11 artyku\u0142\u00f3w naukowych i 10 527 cykli dawstwa kom\u00f3rek jajowych wykaza\u0142o, \u017ce rosn\u0105cy wiek m\u0119\u017cczyzn wi\u0105za\u0142 si\u0119 z niewielkim spadkiem wska\u017anika \u017cywych urodze\u0144.<\/p>\n

Dzieci pocz\u0119te przez starszych m\u0119\u017cczyzn s\u0105 r\u00f3wnie\u017c bardziej nara\u017cone na poronienie, urodzenie martwego dziecka i wcze\u015bniactwo. Podkre\u015bla to b\u0142\u0119dne przekonanie, \u017ce je\u015bli plemniki mog\u0105 p\u0142ywa\u0107 i penetrowa\u0107 kom\u00f3rk\u0119 jajow\u0105, wszystko jest w porz\u0105dku - poj\u0119cie, kt\u00f3re wielu, w tym niekt\u00f3rzy lekarze, nie jest jeszcze w pe\u0142ni zrozumia\u0142e.<\/p>\n

Starsi ojcowie cz\u0119\u015bciej maj\u0105 dzieci z wadami wrodzonymi, niekt\u00f3rymi nowotworami i zaburzeniami neurologicznymi. Badania pokazuj\u0105, \u017ce starsi ojcowie cz\u0119\u015bciej maj\u0105 dzieci z wadami wrodzonymi, takimi jak rozszczep wargi, i s\u0105 bardziej nara\u017ceni na niekt\u00f3re nowotwory wieku dzieci\u0119cego.<\/p>\n

Co zatem kryje si\u0119 za tymi alarmuj\u0105cymi statystykami? Dlaczego widzimy wi\u0119cej starszych ojc\u00f3w w wiadomo\u015bciach, takich jak m\u0119scy celebryci maj\u0105cy dzieci w wieku 70 i 80 lat? Przyczyna le\u017cy w ci\u0105g\u0142ej produkcji spermy przez ca\u0142e \u017cycie m\u0119\u017cczyzny. Sperma jest generowana co oko\u0142o 74 dni, a m\u0119\u017cczy\u017ani nie maj\u0105 jej do\u015b\u0107. Badania sugeruj\u0105 jednak, \u017ce im d\u0142u\u017cej trwa proces produkcji spermy, tym wi\u0119ksze prawdopodobie\u0144stwo wprowadzenia mutacji genetycznych.<\/p>\n

 <\/p>\n

Zrozumienie procesu reprodukcji<\/h2>\n

Produkcja plemnik\u00f3w opiera si\u0119 na spermatogonialnych kom\u00f3rkach macierzystych, kt\u00f3re nieustannie odnawiaj\u0105 si\u0119 poprzez podzia\u0142 kom\u00f3rek. Jednak przy ka\u017cdej replikacji istnieje ryzyko wyst\u0105pienia b\u0142\u0119d\u00f3w kopiowania. Im starszy m\u0119\u017cczyzna, tym wi\u0119cej razy te kom\u00f3rki macierzyste si\u0119 replikuj\u0105, co prowadzi do wi\u0119kszej liczby b\u0142\u0119d\u00f3w. Dzieci starszych ojc\u00f3w mog\u0105 mie\u0107 wi\u0119cej mutacji genetycznych ni\u017c dzieci m\u0142odszych ojc\u00f3w.<\/p>\n

Podczas gdy wi\u0119kszo\u015b\u0107 tych mutacji jest nieszkodliwa, niekt\u00f3re z nich mog\u0105 mie\u0107 powa\u017cne konsekwencje. Mog\u0105 one przyczynia\u0107 si\u0119 do chor\u00f3b genetycznych, dotykaj\u0105c oko\u0142o jednego na 300 \u017cywych urodze\u0144. Te mutacje \"de novo\" s\u0105 odpowiedzialne za r\u00f3\u017cne zaburzenia, w tym achondroplazj\u0119 i zesp\u00f3\u0142 Aperta.<\/p>\n

Ponadto pewn\u0105 rol\u0119 mog\u0105 odgrywa\u0107 zwi\u0105zane z wiekiem zmiany w znakach epigenetycznych wyst\u0119puj\u0105cych na DNA w ludzkich plemnikach. Te znaki epigenetyczne kontroluj\u0105 ekspresj\u0119 gen\u00f3w i mog\u0105 by\u0107 modyfikowane przez r\u00f3\u017cne czynniki \u015brodowiskowe. Zmiany te s\u0105 zwi\u0105zane nie tylko z rozwojem plemnik\u00f3w, ale tak\u017ce z rozwojem uk\u0142adu nerwowego, chocia\u017c dok\u0142adne przyczyny pozostaj\u0105 niejasne.<\/p>\n

 <\/p>\n

Wiek ojca i potrzeba \u015bwiadomo\u015bci<\/h2>\n

To oczywiste, \u017ce Wiek ojca ma znaczenie<\/a>Coraz wi\u0119cej m\u0119\u017cczyzn decyduje si\u0119 na ojcostwo w starszym wieku. Po\u0142\u0105czenie czynnik\u00f3w, w tym op\u00f3\u017anionych ma\u0142\u017ce\u0144stw, drugich ma\u0142\u017ce\u0144stw, wspomaganej reprodukcji i zmieniaj\u0105cych si\u0119 norm spo\u0142ecznych, doprowadzi\u0142o do tego, \u017ce coraz wi\u0119cej m\u0119\u017cczyzn staje si\u0119 starszymi ojcami. Ale jak widzieli\u015bmy, nie jest to bez konsekwencji.<\/p>\n

W tym krajobrazie firmy takie jak ExSeed wprowadzi\u0142y innowacyjne rozwi\u0105zania, aby pom\u00f3c m\u0119\u017cczyznom w ocenie i monitorowaniu ich p\u0142odno\u015bci w wygodny spos\u00f3b z domu. The Domowy test nasienia ExSeed<\/a>w po\u0142\u0105czeniu z aplikacj\u0105 na smartfona, zapewnia m\u0119\u017cczyznom mo\u017cliwo\u015b\u0107 oceny ruchliwo\u015bci, koncentracji i og\u00f3lnej jako\u015bci nasienia, a wszystko to w zaciszu w\u0142asnej przestrzeni. Dzi\u0119ki temu m\u0119\u017cczy\u017ani mog\u0105 przej\u0105\u0107 kontrol\u0119 nad swoim zdrowiem reprodukcyjnym.<\/p>","protected":false},"excerpt":{"rendered":"

When we think of the effects of age on fertility, our minds often gravitate towards women, focusing on the declining egg supply, chromosomal issues, and infertility. One study even found that 1 in 5 men consider infertility to be only a woman’s issue. But here’s something that’s not talked about as often \u2013 the impact […]<\/p>\n","protected":false},"author":3,"featured_media":126791,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"content-type":"","footnotes":""},"categories":[198,201],"tags":[],"class_list":["post-120937","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-mens-fertility","category-mind-body"],"acf":[],"yoast_head":"\nDo Men Have Biological Clocks? Male Fertility and Age<\/title>\n<meta name=\"description\" content=\"Age and fertility are often discussed in relation to women and those with wombs, but men and people producing sperm are not immune from time.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.exseedhealth.com\/pl\/mens-biological-clock\/\" \/>\n<meta property=\"og:locale\" content=\"pl_PL\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Do Men Have Biological Clocks? Male Fertility and Age\" \/>\n<meta property=\"og:description\" content=\"Age and fertility are often discussed in relation to women and those with wombs, but men and people producing sperm are not immune from time.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.exseedhealth.com\/pl\/mens-biological-clock\/\" \/>\n<meta property=\"og:site_name\" content=\"ExSeed Health\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/ExSeedHealth\" \/>\n<meta property=\"article:published_time\" content=\"2023-10-21T09:55:36+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2024-03-20T16:06:31+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.exseedhealth.com\/wp-content\/uploads\/2023\/10\/Blog-Image-Upload-Size-1920x1080-97.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1920\" \/>\n\t<meta property=\"og:image:height\" content=\"1080\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Emil Andersen, PhD\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@ExSeed_Health\" \/>\n<meta name=\"twitter:site\" content=\"@ExSeed_Health\" \/>\n<meta name=\"twitter:label1\" content=\"Napisane przez\" \/>\n\t<meta name=\"twitter:data1\" content=\"Emil Andersen, PhD\" \/>\n\t<meta name=\"twitter:label2\" content=\"Szacowany czas czytania\" \/>\n\t<meta name=\"twitter:data2\" content=\"4 minuty\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.exseedhealth.com\\\/mens-biological-clock\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.exseedhealth.com\\\/mens-biological-clock\\\/\"},\"author\":{\"name\":\"Emil Andersen, PhD\",\"@id\":\"https:\\\/\\\/www.exseedhealth.com\\\/#\\\/schema\\\/person\\\/5d08eb43d90734a01dcf3cb77ce5e109\"},\"headline\":\"Do Men Have Biological Clocks? 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