{"id":101943,"date":"2023-03-14T16:18:58","date_gmt":"2023-03-14T16:18:58","guid":{"rendered":"https:\/\/www.exseedhealth.com\/?p=101943"},"modified":"2024-03-21T10:56:40","modified_gmt":"2024-03-21T10:56:40","slug":"cystic-fibrosis-male-fertility","status":"publish","type":"post","link":"https:\/\/www.exseedhealth.com\/pl\/cystic-fibrosis-male-fertility\/","title":{"rendered":"Mukowiscydoza i m\u0119ska p\u0142odno\u015b\u0107"},"content":{"rendered":"<p>Mukowiscydoza to choroba, kt\u00f3ra dotyka oko\u0142o 100 000 os\u00f3b na ca\u0142ym \u015bwiecie - a 50% z nich to m\u0119\u017cczy\u017ani. Choroba ta ma daleko id\u0105cy wp\u0142yw na zdrowie i styl \u017cycia os\u00f3b, kt\u00f3re na ni\u0105 cierpi\u0105 - ale czy mo\u017ce wp\u0142ywa\u0107 na p\u0142odno\u015b\u0107?<\/p>\n<p>&nbsp;<\/p>\n<h2>Co to jest mukowiscydoza?<\/h2>\n<p>Mukowiscydoza (czasami znana jako CF) jest chorob\u0105, kt\u00f3ra powoduje powa\u017cne uszkodzenie p\u0142uc, a tak\u017ce wp\u0142ywa na uk\u0142ad trawienny i inne narz\u0105dy w organizmie. Zaburzenie to wp\u0142ywa na produkcj\u0119 \u015bluzu, potu i sok\u00f3w trawiennych w \u017co\u0142\u0105dku.<\/p>\n<p>W przypadku os\u00f3b bez mukowiscydozy p\u0142yny te s\u0105 zazwyczaj cienkie i \u015bliskie. Jednak osoby z mukowiscydoz\u0105 maj\u0105 wadliwy gen, kt\u00f3ry powoduje, \u017ce p\u0142yny te staj\u0105 si\u0119 g\u0119ste i lepkie. Powoduje to gromadzenie si\u0119 \u015bluzu w p\u0142ucach i trzustce, co oznacza, \u017ce rurki, kana\u0142y i przej\u015bcia zostaj\u0105 zatkane. Utrudnia to oddychanie, a tak\u017ce wp\u0142ywa na inne funkcje organizmu.<\/p>\n<p>Problemy z uk\u0142adem oddechowym s\u0105 spowodowane gromadzeniem si\u0119 \u015bluzu w p\u0142ucach, a osoby z mukowiscydoz\u0105 cz\u0119sto maj\u0105 duszno\u015bci i zmagaj\u0105 si\u0119 z nawracaj\u0105cymi infekcjami klatki piersiowej. Osoby z mukowiscydoz\u0105 cz\u0119sto maj\u0105 r\u00f3wnie\u017c r\u00f3\u017cne problemy trawienne - dzieje si\u0119 tak, poniewa\u017c \u015bluz zatyka r\u00f3wnie\u017c trzustk\u0119, uniemo\u017cliwiaj\u0105c enzymom potrzebnym do prawid\u0142owego trawienia dotarcie do jelit.<\/p>\n<p>Osoby chore na mukowiscydoz\u0119 maj\u0105 niestety ni\u017csz\u0105 \u015bredni\u0105 d\u0142ugo\u015b\u0107 \u017cycia, jednak dzi\u0119ki post\u0119powi medycyny \u017cyj\u0105 d\u0142u\u017cej, a niekt\u00f3rym udaje si\u0119 prowadzi\u0107 stosunkowo normalne \u017cycie - cho\u0107 wymagaj\u0105 codziennej opieki i regularnych interwencji medycznych.<\/p>\n<p>&nbsp;<\/p>\n<h2>Czy mukowiscydoza jest dziedziczna?<\/h2>\n<p>Mukowiscydoza jest chorob\u0105 dziedziczn\u0105, spowodowan\u0105 wadliwym genem, kt\u00f3ry wp\u0142ywa na spos\u00f3b, w jaki s\u00f3l i woda przemieszczaj\u0105 si\u0119 do i z kom\u00f3rek. Na mukowiscydoz\u0119 nie mo\u017cna si\u0119 \"zarazi\u0107\", ale mo\u017cna si\u0119 z ni\u0105 urodzi\u0107, je\u015bli oboje rodzice s\u0105 nosicielami wadliwego genu.<\/p>\n<p>Szacuje si\u0119, \u017ce 1 na 25 os\u00f3b w Wielkiej Brytanii jest nosicielem recesywnego genu mukowiscydozy. Nie musi to oznacza\u0107, \u017ce rodzic sam b\u0119dzie mia\u0142 mukowiscydoz\u0119.<\/p>\n<p>Je\u015bli oboje rodzice s\u0105 nosicielami, istnieje ryzyko:<\/p>\n<ul>\n<li>Szansa 50%, \u017ce dziecko odziedziczy wadliwy gen od jednego z rodzic\u00f3w i stanie si\u0119 jego nosicielem.<\/li>\n<li>Szansa 25%, \u017ce dziecko nie odziedziczy \u017cadnych wadliwych gen\u00f3w i nie zachoruje na mukowiscydoz\u0119 lub nie b\u0119dzie w stanie przekaza\u0107 jej dalej.<\/li>\n<li>Szansa 25%, \u017ce dziecko odziedziczy wadliwy gen od obojga rodzic\u00f3w i samo zachoruje na mukowiscydoz\u0119.<\/li>\n<\/ul>\n<p>Je\u015bli jedno z rodzic\u00f3w ma mukowiscydoz\u0119, a drugie jest nosicielem, istnieje ryzyko:<\/p>\n<ul>\n<li>50% szansa, \u017ce dziecko b\u0119dzie nosicielem wadliwego genu, ale nie b\u0119dzie cierpia\u0142o na chorob\u0119.<\/li>\n<li>50% szansa, \u017ce dziecko b\u0119dzie mia\u0142o mukowiscydoz\u0119<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h2>Czy mukowiscydoza wp\u0142ywa na p\u0142odno\u015b\u0107 kobiet?<\/h2>\n<p>Og\u00f3lnie rzecz bior\u0105c, kobiety z mukowiscydoz\u0105 s\u0105 nadal p\u0142odne i zdecydowana wi\u0119kszo\u015b\u0107 z nich jest w stanie zaj\u015b\u0107 w ci\u0105\u017c\u0119 w spos\u00f3b naturalny po 12 miesi\u0105cach stara\u0144. Istnieje jednak kilka skutk\u00f3w ubocznych choroby, kt\u00f3re mog\u0105 nieco utrudni\u0107 zaj\u015bcie w ci\u0105\u017c\u0119.<\/p>\n<p>Po pierwsze, ich \u015bluz szyjkowy jest cz\u0119sto g\u0119stszy ni\u017c \u015bluz osoby, kt\u00f3ra nie cierpi na t\u0119 chorob\u0119. \u015aluz szyjkowy odgrywa wa\u017cn\u0105 rol\u0119 w pomaganiu plemnikom w dotarciu do kom\u00f3rki jajowej, a gdy jest g\u0119sty i lepki, mo\u017ce im to utrudni\u0107!<\/p>\n<p>Problemy trawienne zwi\u0105zane z mukowiscydoz\u0105 mog\u0105 r\u00f3wnie\u017c powodowa\u0107 problemy z owulacj\u0105, a niekt\u00f3re kobiety z mukowiscydoz\u0105 zauwa\u017caj\u0105, \u017ce maj\u0105 nieregularne cykle miesi\u0105czkowe.<\/p>\n<p>Podczas gdy te dwa czynniki mog\u0105 przyczyni\u0107 si\u0119 do trudniejszej podr\u00f3\u017cy TTC, nadal zdecydowanie mo\u017cliwe jest zaj\u015bcie w ci\u0105\u017c\u0119 i urodzenie zdrowego dziecka, je\u015bli masz mukowiscydoz\u0119. Zesp\u00f3\u0142 medyczny Yoru i specjali\u015bci ds. p\u0142odno\u015bci b\u0119d\u0105 w stanie doradzi\u0107 najlepszy plan dzia\u0142ania, je\u015bli masz trudno\u015bci.<\/p>\n<p>&nbsp;<\/p>\n<h2>Czy mukowiscydoza wp\u0142ywa na p\u0142odno\u015b\u0107 u m\u0119\u017cczyzn?<\/h2>\n<p>Niestety w przypadku m\u0119\u017cczyzn kwestie zwi\u0105zane z mukowiscydoz\u0105 i p\u0142odno\u015bci\u0105 s\u0105 bardziej z\u0142o\u017cone. Ponad <a href=\"https:\/\/www.cff.org\/managing-cf\/fertility-men-cf\">97% m\u0119\u017cczyzn<\/a> z mukowiscydoz\u0105 s\u0105 klasyfikowane jako bezp\u0142odne - chocia\u017c <a href=\"https:\/\/www.cff.org\/managing-cf\/fertility-men-cf\">90%<\/a> z nich mo\u017ce produkowa\u0107 zdrowe plemniki. Co wi\u0119c powoduje problemy z p\u0142odno\u015bci\u0105?<\/p>\n<p>Niep\u0142odno\u015b\u0107 u m\u0119\u017cczyzn z mukowiscydoz\u0105 jest prawie zawsze przypisywana brakowi istotnej cz\u0119\u015bci m\u0119skiego uk\u0142adu rozrodczego - Vas Deferens. Vas Deferens to d\u0142ugi kana\u0142 \u0142\u0105cz\u0105cy naj\u0105drze (zwini\u0119t\u0105 rurk\u0119, kt\u00f3ra przechowuje plemniki po ich wytworzeniu w j\u0105drach) z jam\u0105 miednicy. Rol\u0105 Vas Deferens jest transportowanie dojrza\u0142ych plemnik\u00f3w z naj\u0105drzy do cewki moczowej, gotowych do wytrysku.<\/p>\n<p>Je\u015bli nie masz nasieniowod\u00f3w, prawdopodobnie cierpisz na stan znany jako wrodzony obustronny brak nasieniowod\u00f3w (CBAVD). Jest to niezwykle cz\u0119ste u m\u0119\u017cczyzn z mukowiscydoz\u0105. Je\u015bli masz CBAVD, to nawet je\u015bli produkujesz zdrowe plemniki, nie maj\u0105 one mo\u017cliwo\u015bci przedostania si\u0119 do ejakulatu, co oznacza brak plemnik\u00f3w w pr\u00f3bce nasienia (i brak plemnik\u00f3w zdolnych do zap\u0142odnienia kom\u00f3rki jajowej podczas stosunku p\u0142ciowego).<\/p>\n<p>&nbsp;<\/p>\n<h2>Opcje leczenia niep\u0142odno\u015bci u m\u0119\u017cczyzn z mukowiscydoz\u0105<\/h2>\n<p>Brak plemnik\u00f3w w nasieniu z pewno\u015bci\u0105 utrudni starania o p\u0142odno\u015b\u0107. Ale dobr\u0105 wiadomo\u015bci\u0105 jest to, \u017ce je\u015bli produkujesz zdrowe plemniki, mo\u017cliwe jest posiadanie w\u0142asnych biologicznych dzieci - b\u0119dziesz tylko potrzebowa\u0142 pomocnej d\u0142oni.<\/p>\n<p>Chirurgiczna ekstrakcja plemnik\u00f3w mo\u017ce usun\u0105\u0107 plemniki z j\u0105der lub naj\u0105drzy, kt\u00f3re mog\u0105 by\u0107 wykorzystane w leczeniu wspomaganej p\u0142odno\u015bci, takim jak ICSI i IVF.<\/p>\n<p>Istniej\u0105 r\u00f3\u017cne chirurgiczne opcje ekstrakcji plemnik\u00f3w, w tym.<\/p>\n<p>MESA - mikrochirurgiczna aspiracja nasienia z naj\u0105drza. Operacja wykonywana w znieczuleniu og\u00f3lnym w celu usuni\u0119cia plemnik\u00f3w bezpo\u015brednio z naj\u0105drza.<br \/>\nPESA - przezsk\u00f3rna aspiracja nasienia z naj\u0105drza - podobna do MESA, ale mniej skomplikowana i ta\u0144sza, do pobrania nasienia u\u017cywana jest ig\u0142a, dzi\u0119ki czemu mo\u017cna to zrobi\u0107 w znieczuleniu miejscowym.<br \/>\nTESE - ekstrakcja plemnik\u00f3w z j\u0105der - zabieg chirurgiczny polegaj\u0105cy na pobraniu tkanki bezpo\u015brednio z j\u0105der i ekstrakcji plemnik\u00f3w.<br \/>\nTESA - Aspiracja nasienia z j\u0105der - podobna do TESE, ale wykonywana przy u\u017cyciu ig\u0142y, dzi\u0119ki czemu jest mniej inwazyjna i mo\u017ce by\u0107 wykonywana w znieczuleniu miejscowym.<\/p>\n<p>Je\u015bli podczas kt\u00f3rejkolwiek z powy\u017cszych procedur zostan\u0105 znalezione zdrowe plemniki, mog\u0105 one zosta\u0107 wykorzystane w leczeniu niep\u0142odno\u015bci, a ty jeste\u015b o krok bli\u017cej do stworzenia swojej rodziny.<\/p>\n<p>&nbsp;<\/p>\n<h2>Co je\u015bli jestem nosicielem gen\u00f3w CF? Czy wp\u0142ynie to na moj\u0105 p\u0142odno\u015b\u0107?<\/h2>\n<p>Je\u015bli jeste\u015b nosicielem zmutowanego genu, kt\u00f3ry powoduje mukowiscydoz\u0119, istnieje prawdopodobie\u0144stwo, \u017ce mo\u017ce to mie\u0107 wp\u0142yw na Twoj\u0105 p\u0142odno\u015b\u0107 - nawet je\u015bli nie masz innych objaw\u00f3w choroby. <a href=\"https:\/\/www.fertstert.org\/article\/S0015-0282(10)00308-0\/\">Badania<\/a> wykaza\u0142y, \u017ce m\u0119\u017cczy\u017ani cierpi\u0105cy na azoospermi\u0119 (brak plemnik\u00f3w w nasieniu) s\u0105 dwukrotnie bardziej nara\u017ceni na nosicielstwo zmutowanego genu CF. Niekt\u00f3rzy m\u0119\u017cczy\u017ani b\u0119d\u0105cy nosicielami tego recesywnego genu mog\u0105 mie\u0107 r\u00f3wnie\u017c CBAVD (brak Vas Deferensa).<\/p>\n<p>Dlatego je\u015bli odkryjesz, \u017ce masz <a href=\"https:\/\/www.exseedhealth.com\/pl\/what-is-azoospermia\/\">Azoospermia<\/a>, zaleca si\u0119 poddanie si\u0119 badaniu przesiewowemu na obecno\u015b\u0107 genu CF. Podobnie, je\u015bli odkryjesz, \u017ce jeste\u015b nosicielem genu CF, zdecydowanie powiniene\u015b zbada\u0107 swoj\u0105 sperm\u0119. Wiele os\u00f3b nie wykazuje \u017cadnych zewn\u0119trznych objaw\u00f3w azoospermii i odkrywa brak plemnik\u00f3w w ejakulacie dopiero po rozpocz\u0119ciu stara\u0144 o dziecko.<\/p>\n<p>Je\u015bli chcesz przyj\u0105\u0107 proaktywne podej\u015bcie do swojego zdrowia i p\u0142odno\u015bci, nasze domowe badanie nasienia mo\u017ce Ci w tym pom\u00f3c. Dowiedz si\u0119 wi\u0119cej o naszym <a href=\"https:\/\/www.exseedhealth.com\/pl\/exseed-home-sperm-test\/\">test p\u0142odno\u015bci dla m\u0119\u017cczyzn<\/a> i sprawd\u017a ca\u0142kowit\u0105 liczb\u0119 ruchliwych plemnik\u00f3w.<\/p>","protected":false},"excerpt":{"rendered":"<p>Cystic Fibrosis is a condition that affects around 100,000 people around the world &#8211; and 50% of those are men. The condition has far reaching effects on the health and lifestyle of people who suffer from it &#8211; but can it affect your fertility? &nbsp; What is Cystic Fibrosis? Cystic Fibrosis (sometimes known as CF) [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":101945,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"content-type":"","footnotes":""},"categories":[198,202],"tags":[],"class_list":["post-101943","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-mens-fertility","category-womens-fertility"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v28.2 (Yoast SEO v28.7) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Cystic Fibrosis and Male Fertility<\/title>\n<meta name=\"description\" content=\"Cystic Fibrosis often affects men&#039;s ability to reproduce naturally, thankfully there are methods to overcome apparent infertility, read more!\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" 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