{"id":4382,"date":"2019-01-16T06:13:04","date_gmt":"2019-01-16T06:13:04","guid":{"rendered":"http:\/\/localhost\/neww\/the-sperm-journey-to-the-egg\/"},"modified":"2025-03-06T10:11:21","modified_gmt":"2025-03-06T10:11:21","slug":"the-sperms-journey-to-the-egg","status":"publish","type":"post","link":"https:\/\/www.exseedhealth.com\/fr\/the-sperms-journey-to-the-egg\/","title":{"rendered":"Le voyage des spermatozo\u00efdes vers l'\u0153uf"},"content":{"rendered":"<h2>What is the goal of a sperm cell?<\/h2>\n<p>The goal of the sperms&#8217; journey to the egg is to fertilize it. To do so, the sperm cell must pass through a long and challenging path. This is one of the reasons why the total number of motile sperm cells is very important, and a key parameter for a man\u2019s potential to reach pregnancy with his partner.<\/p>\n<p style=\"text-align: center;\"><strong>Fig 1<img fetchpriority=\"high\" decoding=\"async\" class=\"alignnone wp-image-98330 size-full\" src=\"https:\/\/www.exseedhealth.com\/wp-content\/uploads\/2019\/01\/Sperms-journey-to-the-egg.png\" alt=\"Sperms journey to the egg\" width=\"820\" height=\"807\" srcset=\"https:\/\/www.exseedhealth.com\/wp-content\/uploads\/2019\/01\/Sperms-journey-to-the-egg.png 820w, https:\/\/www.exseedhealth.com\/wp-content\/uploads\/2019\/01\/Sperms-journey-to-the-egg-300x295.png 300w, https:\/\/www.exseedhealth.com\/wp-content\/uploads\/2019\/01\/Sperms-journey-to-the-egg-768x756.png 768w, https:\/\/www.exseedhealth.com\/wp-content\/uploads\/2019\/01\/Sperms-journey-to-the-egg-12x12.png 12w, https:\/\/www.exseedhealth.com\/wp-content\/uploads\/2019\/01\/Sperms-journey-to-the-egg-60x59.png 60w, https:\/\/www.exseedhealth.com\/wp-content\/uploads\/2019\/01\/Sperms-journey-to-the-egg-110x108.png 110w, https:\/\/www.exseedhealth.com\/wp-content\/uploads\/2019\/01\/Sperms-journey-to-the-egg-600x590.png 600w\" sizes=\"(max-width: 820px) 100vw, 820px\" \/><\/strong><\/p>\n<p>The sperms&#8217; journey to the egg begins with millions of sperm cells that are released into the female reproductive tract during intercourse. The sperm cells gain their full ability to swim when they are ejaculated into the reproductive tract <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4594619\/\" target=\"_blank\" rel=\"noopener noreferrer\">[1]<\/a>,<a href=\"https:\/\/academic.oup.com\/humupd\/article\/12\/1\/23\/607817\" target=\"_blank\" rel=\"noopener noreferrer\">[2]<\/a>.<\/p>\n<p>Upon ejaculation, the sperm cells are enclosed in a fluid called seminal plasma or semen, which is a mix of fluids from the testes, seminal vesicles, prostate, and the bulbourethral glands. The fluid contains elements which protect the sperm cells during their journey towards the egg. The semen thickens and helps the sperm cells stay inside the woman &#8211; as close as possible to the cervix, which is the \u201cgate\u201d to the egg. Liquid extends from the cervix, allowing the sperm cells from the semen to swim into the cervix. Only the strongest sperm cells will make it this far. Once through the cervix, the sperm cells swim across the uterus and into the fallopian tubes as illustrated in figure 1.<\/p>\n<p style=\"text-align: center;\"><strong>Fig 2<\/strong><\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"aligncenter wp-image-98331 size-medium\" src=\"https:\/\/www.exseedhealth.com\/wp-content\/uploads\/2019\/01\/Sperm-to-the-egg-300x300.jpg\" alt=\"Sperm to the egg\" width=\"300\" height=\"300\" srcset=\"https:\/\/www.exseedhealth.com\/wp-content\/uploads\/2019\/01\/Sperm-to-the-egg-300x300.jpg 300w, https:\/\/www.exseedhealth.com\/wp-content\/uploads\/2019\/01\/Sperm-to-the-egg-1024x1024.jpg 1024w, https:\/\/www.exseedhealth.com\/wp-content\/uploads\/2019\/01\/Sperm-to-the-egg-150x150.jpg 150w, https:\/\/www.exseedhealth.com\/wp-content\/uploads\/2019\/01\/Sperm-to-the-egg-768x768.jpg 768w, https:\/\/www.exseedhealth.com\/wp-content\/uploads\/2019\/01\/Sperm-to-the-egg-1536x1536.jpg 1536w, https:\/\/www.exseedhealth.com\/wp-content\/uploads\/2019\/01\/Sperm-to-the-egg.jpg 2048w, https:\/\/www.exseedhealth.com\/wp-content\/uploads\/2019\/01\/Sperm-to-the-egg-12x12.jpg 12w, https:\/\/www.exseedhealth.com\/wp-content\/uploads\/2019\/01\/Sperm-to-the-egg-60x60.jpg 60w, https:\/\/www.exseedhealth.com\/wp-content\/uploads\/2019\/01\/Sperm-to-the-egg-110x110.jpg 110w, https:\/\/www.exseedhealth.com\/wp-content\/uploads\/2019\/01\/Sperm-to-the-egg-1320x1320.jpg 1320w, https:\/\/www.exseedhealth.com\/wp-content\/uploads\/2019\/01\/Sperm-to-the-egg-600x600.jpg 600w, https:\/\/www.exseedhealth.com\/wp-content\/uploads\/2019\/01\/Sperm-to-the-egg-100x100.jpg 100w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/p>\n<h2><strong>Only the strongest make it this far<\/strong><\/h2>\n<p>Of the millions of sperm cells deposited during intercourse, only very few have the potential to reach the fallopian tubes. Once inside the tubes, the sperm cells follow signals (a process called chemotaxis) from the supportive cells (called the cumulus cells) of the egg\u00a0<a href=\"https:\/\/www.nature.com\/articles\/nrm1893\" target=\"_blank\" rel=\"noopener noreferrer\">[3]<\/a>. On the way, the sperm cells undergo a series of biochemical and functional changes. These prepare the sperm cells for fertilization.<\/p>\n<p>Eventually, the sperm cells meet a barrier of cumulus cells surrounding the egg. To pass through this barrier, the sperm cells must use their very special \u2018stroke\u2019, known as <em>hyperactivation<\/em>. The sperm cell then has to pass another barrier called the \u2018zona pellucida\u2019, an additional layer of the egg. To pass this barrier the sperm cells now must undergo a process called the <em>acrosome reaction<\/em>. That&#8217;s where a deposit at the top of the sperm cell releases enzymes.\u00a0These enzymes will break down the zona pellucida barrier, allowing the sperm to penetrate the egg <a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1111\/j.1365-2605.2006.00681.x\" target=\"_blank\" rel=\"noopener noreferrer\">[4]<\/a>, <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S001502821641959X?via%3Dihub\" target=\"_blank\" rel=\"noopener noreferrer\">[5]<\/a>. See figure 2.<\/p>\n<p>When the sperm cell\u2019s head is inside the egg, the tail of the sperm detaches. At that moment, the zona pellucida becomes impermeable to other sperm cells.<\/p>\n<p>When inside the egg, both the egg and the sperm prepare for a genetic fusion. After this, the 23 chromosomes from the egg and the sperm cell respectively, fuse together. They generate\u00a0the 1<sup>st<\/sup> cell that gives rise to new life, called the zygote.<\/p>\n<p>After fertilization, the zygote moves through the fallopian tube to attach itself to the inner wall of the uterus.<\/p>\n<h2><strong>What about twins? Is the sperms&#8217; journey to the egg different?<\/strong><\/h2>\n<p>Twin pregnancies happen either when two fertilized eggs attaches to the uterus simultaneously (dizygotic twins). Or it happens when one fertilized egg splits into two embryos (monozygotic twins).<\/p>\n<p>With the ExSeed <a href=\"https:\/\/www.exseedhealth.com\/exseed-home-sperm-test\/\" target=\"_blank\" rel=\"noopener noreferrer\">Home Sperm Test<\/a>, we assess how many sperm cells there are in a semen sample and how many of them are swimming.\u00a0As you may see from this post, these are important parameters in determining if the sperm cells will reach the egg.<\/p>\n<p><a href=\"\/contact-us\/\" target=\"_blank\" rel=\"noopener noreferrer\">As always, don\u2019t hesitate to contact us if you have any comments or questions!<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>What is the goal of a sperm cell? The goal of the sperms&#8217; journey to the egg is to fertilize it. To do so, the sperm cell must pass through a long and challenging path. This is one of the reasons why the total number of motile sperm cells is very important, and a key [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":126434,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"content-type":"","footnotes":""},"categories":[198,202],"tags":[48,49,50,51,52,53,55,56,57,58,59,60,61],"class_list":["post-4382","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-mens-fertility","category-womens-fertility","tag-accurate","tag-analysis","tag-consultation","tag-ex-seed","tag-exseed-health","tag-fertility","tag-healthy","tag-home-sperm-testing","tag-male-fertility","tag-medical","tag-men","tag-quality","tag-sperm-test"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v28.2 (Yoast SEO v28.7) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>The Sperms&#039; Journey to the Egg<\/title>\n<meta name=\"description\" content=\"The goal of a sperm cell is to fertilize the egg. 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The sperms journey to the egg is a long and challenging path that not all sperms reach.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.exseedhealth.com\/fr\/the-sperms-journey-to-the-egg\/\" \/>\n<meta property=\"og:site_name\" content=\"ExSeed Health\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/ExSeedHealth\" \/>\n<meta property=\"article:published_time\" content=\"2019-01-16T06:13:04+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2025-03-06T10:11:21+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.exseedhealth.com\/wp-content\/uploads\/2019\/01\/Blog-Image-Upload-Size-1920x1080-86.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1920\" \/>\n\t<meta property=\"og:image:height\" content=\"1080\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Emil Andersen, PhD\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@ExSeed_Health\" \/>\n<meta name=\"twitter:site\" content=\"@ExSeed_Health\" \/>\n<meta name=\"twitter:label1\" content=\"\u00c9crit par\" \/>\n\t<meta name=\"twitter:data1\" content=\"Emil Andersen, PhD\" \/>\n\t<meta name=\"twitter:label2\" content=\"Dur\u00e9e de lecture estim\u00e9e\" \/>\n\t<meta name=\"twitter:data2\" content=\"4 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.exseedhealth.com\\\/the-sperms-journey-to-the-egg\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.exseedhealth.com\\\/the-sperms-journey-to-the-egg\\\/\"},\"author\":{\"name\":\"Emil Andersen, PhD\",\"@id\":\"https:\\\/\\\/www.exseedhealth.com\\\/#\\\/schema\\\/person\\\/5d08eb43d90734a01dcf3cb77ce5e109\"},\"headline\":\"The Sperms&#8217; Journey to the Egg\",\"datePublished\":\"2019-01-16T06:13:04+00:00\",\"dateModified\":\"2025-03-06T10:11:21+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.exseedhealth.com\\\/the-sperms-journey-to-the-egg\\\/\"},\"wordCount\":593,\"commentCount\":20,\"publisher\":{\"@id\":\"https:\\\/\\\/www.exseedhealth.com\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/www.exseedhealth.com\\\/the-sperms-journey-to-the-egg\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.exseedhealth.com\\\/wp-content\\\/uploads\\\/2019\\\/01\\\/Blog-Image-Upload-Size-1920x1080-86.jpg\",\"keywords\":[\"accurate\",\"analysis\",\"consultation\",\"ex seed\",\"Exseed health\",\"fertility\",\"healthy\",\"Home Sperm Testing\",\"male fertility\",\"medical\",\"men\",\"quality\",\"sperm test\"],\"articleSection\":[\"Men\u2019s Fertility\",\"Women\u2019s Fertility\"],\"inLanguage\":\"fr-FR\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/www.exseedhealth.com\\\/the-sperms-journey-to-the-egg\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.exseedhealth.com\\\/the-sperms-journey-to-the-egg\\\/\",\"url\":\"https:\\\/\\\/www.exseedhealth.com\\\/the-sperms-journey-to-the-egg\\\/\",\"name\":\"The Sperms' Journey to the Egg\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.exseedhealth.com\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/www.exseedhealth.com\\\/the-sperms-journey-to-the-egg\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/www.exseedhealth.com\\\/the-sperms-journey-to-the-egg\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.exseedhealth.com\\\/wp-content\\\/uploads\\\/2019\\\/01\\\/Blog-Image-Upload-Size-1920x1080-86.jpg\",\"datePublished\":\"2019-01-16T06:13:04+00:00\",\"dateModified\":\"2025-03-06T10:11:21+00:00\",\"description\":\"The goal of a sperm cell is to fertilize the egg. 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Il est r\u00e9put\u00e9 pour \u00eatre l'auteur principal de l'\u00e9tude la plus compl\u00e8te \u00e0 ce jour sur l'impact de la perte de poids sur la qualit\u00e9 du sperme. Pendant son mandat \u00e0 l'universit\u00e9 de Cambridge, Emil a men\u00e9 des recherches novatrices ax\u00e9es sur le d\u00e9cryptage des m\u00e9canismes fondamentaux des spermatozo\u00efdes et le d\u00e9veloppement de m\u00e9thodes permettant d'\u00e9valuer leur potentiel de fertilit\u00e9. 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