{"id":150021,"date":"2025-07-31T15:42:03","date_gmt":"2025-07-31T14:42:03","guid":{"rendered":"https:\/\/www.exseedhealth.com\/?p=150021"},"modified":"2025-11-12T14:08:30","modified_gmt":"2025-11-12T14:08:30","slug":"autoimmune-diseases-in-men-how-they-impact-male-fertility","status":"publish","type":"post","link":"https:\/\/www.exseedhealth.com\/es\/autoimmune-diseases-in-men-how-they-impact-male-fertility\/","title":{"rendered":"Enfermedades autoinmunes en el hombre: c\u00f3mo afectan a la fertilidad masculina"},"content":{"rendered":"<p>Las enfermedades autoinmunes afectan a millones de personas en todo el mundo, y algunas de ellas aparecen con mayor frecuencia o gravedad en los hombres. Estas afecciones suelen causar inflamaci\u00f3n y problemas org\u00e1nicos, pero tambi\u00e9n afectan a la fertilidad, un efecto secundario que a menudo se pasa por alto. A continuaci\u00f3n, exploramos cinco enfermedades autoinmunes que son m\u00e1s comunes en los hombres y explicamos c\u00f3mo cada una de ellas puede perjudicar la salud reproductiva.<\/p>\n<h2>Espondilitis anquilosante (EA)<\/h2>\n<p><strong>Lo que es:<\/strong><br \/>\nLa espondilitis anquilosante es un tipo de artritis inflamatoria que afecta principalmente a las articulaciones de la columna vertebral y la zona lumbar. Suele comenzar en los primeros a\u00f1os de la edad adulta y es entre dos y tres veces m\u00e1s frecuente en los hombres (<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Braun%20J%2C%20Sieper%20J.%20Ankylosing%20spondylitis.%20Lancet.%202007%20Apr%2021%3B369%289570%29%3A1379%E2%80%9390.\" target=\"_blank\" rel=\"noopener noreferrer\">Braun y Sieper, 2007<\/a>).<\/p>\n<p><strong>Impacto en la fertilidad:<\/strong><\/p>\n<ul>\n<li>La inflamaci\u00f3n cr\u00f3nica aumenta el estr\u00e9s oxidativo, que puede da\u00f1ar la forma, el movimiento y el ADN de los espermatozoides (<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Ricci%20G%2C%20et%20al.%20Semen%20quality%20in%20young%20men%20with%20ankylosing%20spondylitis%20treated%20with%20NSAIDs%20or%20TNF-%CE%B1%20inhibitors.%20Fertil%20Steril.%202009.\" target=\"_blank\" rel=\"noopener noreferrer\">Ricci et al., 2009<\/a>).<\/li>\n<li>Las hormonas inflamatorias pueden reducir la testosterona y ralentizar la producci\u00f3n de esperma.<\/li>\n<li>El dolor, la rigidez y la fatiga suelen provocar problemas de erecci\u00f3n y disminuci\u00f3n de la libido.<\/li>\n<li>Los f\u00e1rmacos llamados inhibidores del TNF (como etanercept o adalimumab) parecen seguros para la fertilidad e incluso pueden mejorar la salud de los espermatozoides (<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Mahmoud%20AM%2C%20et%20al.%20Effects%20of%20etanercept%20on%20male%20fertility%20in%20patients%20with%20AS.%20Rheumatol%20Int.%202011.\" target=\"_blank\" rel=\"noopener noreferrer\">Mahmoud et al., 2011<\/a>).<\/li>\n<\/ul>\n<h2>Psoriasis y artritis psori\u00e1sica (PsA)<\/h2>\n<p><strong>Lo que es:<\/strong><br \/>\nLa psoriasis es una enfermedad cut\u00e1nea de larga duraci\u00f3n que causa manchas rojas y escamosas. Alrededor del 30% de las personas con psoriasis desarrollan tambi\u00e9n artritis psori\u00e1sica, que causa dolor e hinchaz\u00f3n de las articulaciones. Estas enfermedades suelen aparecer antes y progresar m\u00e1s r\u00e1pidamente en los hombres.<\/p>\n<p><strong>Impacto en la fertilidad:<\/strong><\/p>\n<ul>\n<li>La inflamaci\u00f3n aumenta el estr\u00e9s oxidativo en el semen, lo que puede reducir el recuento y el movimiento de los espermatozoides.<\/li>\n<li>Los s\u00edntomas cut\u00e1neos visibles y el dolor pueden afectar a la confianza y llevar a evitar las relaciones sexuales.<\/li>\n<li>Las sustancias qu\u00edmicas inflamatorias como el TNF-alfa y la IL-17 pueden alterar el equilibrio hormonal y reducir la testosterona.<\/li>\n<li>Los tratamientos que bloquean estas citocinas, como los inhibidores del TNF o la IL-17, suelen ser seguros para los hombres que desean tener hijos (<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Micu%20MC%2C%20et%20al.%20Effects%20of%20IL-17%20and%20TNF%20inhibitors%20on%20male%20reproductive%20function.%20Reprod%20Biol%20Endocrinol.%202023.\" target=\"_blank\" rel=\"noopener noreferrer\">Micu y otros, 2023<\/a>).<\/li>\n<\/ul>\n<h2>Artritis reumatoide (AR)<\/h2>\n<p><strong>Lo que es:<\/strong><br \/>\nLa artritis reumatoide es una enfermedad autoinmune que ataca principalmente a las articulaciones, pero que tambi\u00e9n puede afectar a todo el cuerpo. Aunque es m\u00e1s frecuente en mujeres, los hombres suelen padecer una forma m\u00e1s agresiva de la enfermedad.<\/p>\n<p><strong>Impacto en la fertilidad:<\/strong><\/p>\n<ul>\n<li>Los hombres con AR suelen tener niveles m\u00e1s bajos de testosterona y m\u00e1s altos de LH, un signo de desequilibrio hormonal (<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Kiss%20E%2C%20et%20al.%20Hormonal%20disturbances%20in%20men%20with%20rheumatoid%20arthritis.%20Clin%20Rheumatol.%202005.\" target=\"_blank\" rel=\"noopener noreferrer\">Kiss et al., 2005<\/a>).<\/li>\n<li>La inflamaci\u00f3n continua puede da\u00f1ar el ADN del esperma y reducir su calidad.<\/li>\n<li>La depresi\u00f3n, la fatiga y el dolor articular pueden disminuir la libido y afectar al rendimiento sexual.<\/li>\n<li>Los f\u00e1rmacos habituales para la AR, incluidos el metotrexato y los biol\u00f3gicos, no suelen ser perjudiciales para la fertilidad, pero a veces los m\u00e9dicos aconsejan tomarse un breve descanso antes de intentar concebir.<\/li>\n<\/ul>\n<h2>Diabetes mellitus de tipo 1 (DMT1)<\/h2>\n<p><strong>Lo que es:<\/strong><br \/>\nLa diabetes de tipo 1 es una enfermedad autoinmune que destruye las c\u00e9lulas productoras de insulina del p\u00e1ncreas. Suele comenzar en la infancia o la adolescencia y requiere tratamiento diario con insulina.<\/p>\n<p><strong>Impacto en la fertilidad:<\/strong><\/p>\n<ul>\n<li>Un nivel elevado de az\u00facar en sangre aumenta el estr\u00e9s oxidativo y da\u00f1a los vasos sangu\u00edneos peque\u00f1os, lo que puede da\u00f1ar el ADN de los espermatozoides y reducir su movilidad (<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Agbaje%20IM%2C%20et%20al.%20Increased%20sperm%20DNA%20damage%20in%20diabetic%20men.%20Reprod%20Biomed%20Online.%202007.\" target=\"_blank\" rel=\"noopener noreferrer\">Agbaje et al., 2007<\/a>).<\/li>\n<li>El da\u00f1o nervioso puede causar disfunci\u00f3n er\u00e9ctil o eyaculaci\u00f3n retr\u00f3grada.<\/li>\n<li>Un mal control de la glucosa puede alterar las hormonas y reducir la testosterona.<\/li>\n<li>El tratamiento con insulina en s\u00ed no perjudica la fertilidad, pero mantener constante el nivel de az\u00facar en sangre protege la salud reproductiva.<\/li>\n<\/ul>\n<h2>Colangitis esclerosante primaria (CEP)<\/h2>\n<p><strong>Lo que es:<\/strong><br \/>\nLa CEP es una enfermedad hep\u00e1tica cr\u00f3nica que causa inflamaci\u00f3n y cicatrizaci\u00f3n de los conductos biliares. Afecta m\u00e1s a los hombres que a las mujeres y suele ir acompa\u00f1ada de colitis ulcerosa, una enfermedad inflamatoria intestinal.<\/p>\n<p><strong>Impacto en la fertilidad:<\/strong><\/p>\n<ul>\n<li>Los problemas hep\u00e1ticos pueden interferir en el equilibrio hormonal, disminuyendo la testosterona y el deseo sexual.<\/li>\n<li>La fatiga constante puede causar dificultades sexuales y reducir la motivaci\u00f3n.<\/li>\n<li>Aunque los datos son limitados, es probable que la inflamaci\u00f3n contribuya al da\u00f1o oxidativo del esperma.<\/li>\n<li>F\u00e1rmacos como el \u00e1cido ursodesoxic\u00f3lico (UDCA) y los bloqueantes del TNF utilizados para la EII parecen generalmente seguros para la fertilidad masculina.<\/li>\n<\/ul>\n<h2>Conclusi\u00f3n<\/h2>\n<p>Las enfermedades autoinmunitarias plantean muchos retos a los hombres: no s\u00f3lo dolor y fatiga, sino tambi\u00e9n posibles efectos sobre la fertilidad. La inflamaci\u00f3n, el estr\u00e9s oxidativo y los cambios hormonales pueden da\u00f1ar el esperma y afectar a la salud sexual. Sin embargo, hay buenas noticias: la mayor\u00eda de los tratamientos modernos, especialmente los f\u00e1rmacos biol\u00f3gicos, parecen seguros para la funci\u00f3n reproductora masculina.<\/p>\n<p><strong>Los hombres con enfermedades autoinmunes pueden utilizar <a href=\"https:\/\/shop.exseedhealth.com\/collections\/male-fertility-test-kits\" target=\"_blank\" rel=\"noopener noreferrer\">kits caseros de an\u00e1lisis de esperma<\/a> seguir la salud de la fertilidad<\/strong> - como el recuento, la forma y la movilidad de los espermatozoides. Las pruebas antes o durante el tratamiento ayudan a los hombres a tomar decisiones con seguridad y a colaborar m\u00e1s estrechamente con sus m\u00e9dicos.<\/p>\n<p>Mediante el control precoz de la actividad de la enfermedad y el seguimiento peri\u00f3dico de la fertilidad, los hombres pueden proteger su salud reproductiva y planificar su futura paternidad con confianza.<\/p>","protected":false},"excerpt":{"rendered":"<p>Autoimmune diseases affect millions of people around the world, and some of them appear more often or more severely in men. These conditions usually cause inflammation and organ problems, but they also affect fertility \u2014 a side effect that\u2019s often overlooked. Below, we explore five autoimmune diseases that are more common in men and explain [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":150025,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"content-type":"","footnotes":""},"categories":[200,198],"tags":[],"class_list":["post-150021","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-lifestyle-environmental","category-mens-fertility"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v28.2 (Yoast SEO v28.7) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>How Autoimmune Diseases Affect Male Fertility<\/title>\n<meta name=\"description\" content=\"Discover how autoimmune diseases impact male fertility, plus how at-home sperm testing can help men monitor reproductive health.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.exseedhealth.com\/es\/autoimmune-diseases-in-men-how-they-impact-male-fertility\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"How Autoimmune Diseases Affect Male Fertility\" \/>\n<meta property=\"og:description\" content=\"Discover how autoimmune diseases impact male fertility, plus how at-home sperm testing can help men monitor reproductive health.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.exseedhealth.com\/es\/autoimmune-diseases-in-men-how-they-impact-male-fertility\/\" \/>\n<meta property=\"og:site_name\" content=\"ExSeed Health\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/ExSeedHealth\" \/>\n<meta property=\"article:published_time\" content=\"2025-07-31T14:42:03+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2025-11-12T14:08:30+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.exseedhealth.com\/wp-content\/uploads\/2025\/07\/Visualizing-the-Impact-of-Autoimmune-Disease-1024x576.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1024\" \/>\n\t<meta property=\"og:image:height\" content=\"576\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"Emil Andersen, PhD\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@ExSeed_Health\" \/>\n<meta name=\"twitter:site\" content=\"@ExSeed_Health\" \/>\n<meta name=\"twitter:label1\" content=\"Escrito por\" \/>\n\t<meta name=\"twitter:data1\" content=\"Emil Andersen, PhD\" \/>\n\t<meta name=\"twitter:label2\" content=\"Tiempo de lectura\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutos\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.exseedhealth.com\\\/autoimmune-diseases-in-men-how-they-impact-male-fertility\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.exseedhealth.com\\\/autoimmune-diseases-in-men-how-they-impact-male-fertility\\\/\"},\"author\":{\"name\":\"Emil Andersen, PhD\",\"@id\":\"https:\\\/\\\/www.exseedhealth.com\\\/#\\\/schema\\\/person\\\/5d08eb43d90734a01dcf3cb77ce5e109\"},\"headline\":\"Autoimmune Diseases in Men: How They Impact Male Fertility\",\"datePublished\":\"2025-07-31T14:42:03+00:00\",\"dateModified\":\"2025-11-12T14:08:30+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.exseedhealth.com\\\/autoimmune-diseases-in-men-how-they-impact-male-fertility\\\/\"},\"wordCount\":690,\"publisher\":{\"@id\":\"https:\\\/\\\/www.exseedhealth.com\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/www.exseedhealth.com\\\/autoimmune-diseases-in-men-how-they-impact-male-fertility\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.exseedhealth.com\\\/wp-content\\\/uploads\\\/2025\\\/07\\\/Visualizing-the-Impact-of-Autoimmune-Disease.png\",\"articleSection\":[\"Lifestyle &amp; 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