{"id":150021,"date":"2025-07-31T15:42:03","date_gmt":"2025-07-31T14:42:03","guid":{"rendered":"https:\/\/www.exseedhealth.com\/?p=150021"},"modified":"2025-11-12T14:08:30","modified_gmt":"2025-11-12T14:08:30","slug":"autoimmune-diseases-in-men-how-they-impact-male-fertility","status":"publish","type":"post","link":"https:\/\/www.exseedhealth.com\/da\/autoimmune-diseases-in-men-how-they-impact-male-fertility\/","title":{"rendered":"Autoimmune sygdomme hos m\u00e6nd: Hvordan de p\u00e5virker mandlig fertilitet"},"content":{"rendered":"<p>Autoimmune sygdomme rammer millioner af mennesker over hele verden, og nogle af dem optr\u00e6der oftere eller mere alvorligt hos m\u00e6nd. Disse tilstande for\u00e5rsager normalt bet\u00e6ndelse og organproblemer, men de p\u00e5virker ogs\u00e5 fertiliteten - en bivirkning, der ofte overses. Nedenfor gennemg\u00e5r vi fem autoimmune sygdomme, som er mere almindelige hos m\u00e6nd, og forklarer, hvordan de hver is\u00e6r kan skade den reproduktive sundhed.<\/p>\n<h2>Ankyloserende spondylitis (AS)<\/h2>\n<p><strong>Hvad det er:<\/strong><br \/>\nAnkyloserende spondylitis er en type inflammatorisk gigt, der hovedsageligt rammer rygs\u00f8jlen og leddene i den nedre del af ryggen. Den begynder ofte i den tidlige voksenalder og forekommer ca. to til tre gange oftere hos m\u00e6nd (<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Braun%20J%2C%20Sieper%20J.%20Ankylosing%20spondylitis.%20Lancet.%202007%20Apr%2021%3B369%289570%29%3A1379%E2%80%9390.\" target=\"_blank\" rel=\"noopener noreferrer\">Braun &amp; Sieper, 2007<\/a>).<\/p>\n<p><strong>Indvirkning p\u00e5 fertilitet:<\/strong><\/p>\n<ul>\n<li>Kronisk inflammation \u00f8ger oxidativ stress, som kan skade s\u00e6dcellernes form, bev\u00e6gelse og DNA (<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Ricci%20G%2C%20et%20al.%20Semen%20quality%20in%20young%20men%20with%20ankylosing%20spondylitis%20treated%20with%20NSAIDs%20or%20TNF-%CE%B1%20inhibitors.%20Fertil%20Steril.%202009.\" target=\"_blank\" rel=\"noopener noreferrer\">Ricci et al. 2009<\/a>).<\/li>\n<li>Inflammatoriske hormoner kan s\u00e6nke testosteronniveauet og bremse s\u00e6dproduktionen.<\/li>\n<li>Smerter, stivhed og tr\u00e6thed f\u00f8rer ofte til rejsningsproblemer og nedsat libido.<\/li>\n<li>L\u00e6gemidler kaldet TNF-h\u00e6mmere (s\u00e5som etanercept eller adalimumab) virker sikre for fertiliteten og kan endda forbedre s\u00e6dcellernes sundhed (<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Mahmoud%20AM%2C%20et%20al.%20Effects%20of%20etanercept%20on%20male%20fertility%20in%20patients%20with%20AS.%20Rheumatol%20Int.%202011.\" target=\"_blank\" rel=\"noopener noreferrer\">Mahmoud et al. 2011<\/a>).<\/li>\n<\/ul>\n<h2>Psoriasis og psoriasisgigt (PsA)<\/h2>\n<p><strong>Hvad det er:<\/strong><br \/>\nPsoriasis er en langvarig hudsygdom, der giver r\u00f8de, sk\u00e6llende pletter. Omkring 30% af mennesker med psoriasis udvikler ogs\u00e5 psoriasisgigt, som giver ledsmerter og h\u00e6velser. Disse tilstande har en tendens til at dukke op tidligere og udvikle sig hurtigere hos m\u00e6nd.<\/p>\n<p><strong>Indvirkning p\u00e5 fertilitet:<\/strong><\/p>\n<ul>\n<li>Inflammation \u00f8ger det oxidative stress i s\u00e6den, hvilket kan reducere antallet af s\u00e6dceller og deres bev\u00e6gelse.<\/li>\n<li>Synlige hudsymptomer og smerter kan p\u00e5virke selvtilliden og f\u00f8re til, at man undg\u00e5r sex.<\/li>\n<li>Inflammatoriske kemikalier som TNF-alfa og IL-17 kan forstyrre hormonbalancen og reducere testosteron.<\/li>\n<li>Behandlinger, der blokerer disse cytokiner, s\u00e5som TNF- eller IL-17-h\u00e6mmere, er generelt sikre for m\u00e6nd, der \u00f8nsker at f\u00e5 b\u00f8rn (<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Micu%20MC%2C%20et%20al.%20Effects%20of%20IL-17%20and%20TNF%20inhibitors%20on%20male%20reproductive%20function.%20Reprod%20Biol%20Endocrinol.%202023.\" target=\"_blank\" rel=\"noopener noreferrer\">Micu et al. 2023<\/a>).<\/li>\n<\/ul>\n<h2>Reumatoid arthritis (RA)<\/h2>\n<p><strong>Hvad det er:<\/strong><br \/>\nReumatoid artrit er en autoimmun sygdom, der prim\u00e6rt angriber leddene, men som ogs\u00e5 kan p\u00e5virke hele kroppen. Selvom det er mere almindeligt hos kvinder, oplever m\u00e6nd ofte en mere aggressiv form for sygdommen.<\/p>\n<p><strong>Indvirkning p\u00e5 fertilitet:<\/strong><\/p>\n<ul>\n<li>M\u00e6nd med leddegigt har ofte lavere testosteron- og h\u00f8jere LH-niveauer, hvilket er et tegn p\u00e5 hormonel ubalance (<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Kiss%20E%2C%20et%20al.%20Hormonal%20disturbances%20in%20men%20with%20rheumatoid%20arthritis.%20Clin%20Rheumatol.%202005.\" target=\"_blank\" rel=\"noopener noreferrer\">Kiss et al. 2005<\/a>).<\/li>\n<li>Vedvarende inflammation kan skade s\u00e6dcellernes DNA og forringe deres kvalitet.<\/li>\n<li>Depression, tr\u00e6thed og ledsmerter kan s\u00e6nke libido og p\u00e5virke den seksuelle ydeevne.<\/li>\n<li>Almindelige l\u00e6gemidler mod leddegigt, herunder methotrexat og biologiske l\u00e6gemidler, skader normalt ikke fertiliteten, men l\u00e6ger anbefaler nogle gange, at man holder en kort pause, f\u00f8r man fors\u00f8ger at blive gravid.<\/li>\n<\/ul>\n<h2>Type 1-diabetes mellitus (T1DM)<\/h2>\n<p><strong>Hvad det er:<\/strong><br \/>\nType 1-diabetes er en autoimmun tilstand, der \u00f8del\u00e6gger de insulinproducerende celler i bugspytkirtlen. Den starter som regel i barndommen eller teenage\u00e5rene og kr\u00e6ver daglig insulinbehandling.<\/p>\n<p><strong>Indvirkning p\u00e5 fertilitet:<\/strong><\/p>\n<ul>\n<li>H\u00f8jt blodsukker \u00f8ger det oxidative stress og beskadiger de sm\u00e5 blodkar, hvilket kan skade s\u00e6dcellernes DNA og reducere deres bev\u00e6gelighed (<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Agbaje%20IM%2C%20et%20al.%20Increased%20sperm%20DNA%20damage%20in%20diabetic%20men.%20Reprod%20Biomed%20Online.%202007.\" target=\"_blank\" rel=\"noopener noreferrer\">Agbaje et al. 2007<\/a>).<\/li>\n<li>Nerveskade kan for\u00e5rsage erektil dysfunktion eller retrograd ejakulation.<\/li>\n<li>D\u00e5rlig glukosekontrol kan forstyrre hormonerne og s\u00e6nke testosteronniveauet.<\/li>\n<li>Insulinbehandling i sig selv skader ikke fertiliteten, men at holde blodsukkeret stabilt beskytter den reproduktive sundhed.<\/li>\n<\/ul>\n<h2>Prim\u00e6r skleroserende cholangitis (PSC)<\/h2>\n<p><strong>Hvad det er:<\/strong><br \/>\nPSC er en kronisk leversygdom, der for\u00e5rsager bet\u00e6ndelse og ardannelse i galdegangene. Den rammer oftere m\u00e6nd end kvinder og optr\u00e6der ofte sammen med colitis ulcerosa, en inflammatorisk tarmsygdom.<\/p>\n<p><strong>Indvirkning p\u00e5 fertilitet:<\/strong><\/p>\n<ul>\n<li>Leverproblemer kan forstyrre hormonbalancen og s\u00e6nke testosteronniveauet og sexlysten.<\/li>\n<li>Konstant tr\u00e6thed kan give seksuelle problemer og mindske motivationen.<\/li>\n<li>Selvom data er begr\u00e6nsede, bidrager inflammation sandsynligvis til oxidativ s\u00e6dskade.<\/li>\n<li>L\u00e6gemidler som ursodeoxycholsyre (UDCA) og TNF-blokkere, der bruges til IBD, virker generelt sikre for den mandlige fertilitet.<\/li>\n<\/ul>\n<h2>Konklusion<\/h2>\n<p>Autoimmune sygdomme giver mange udfordringer for m\u00e6nd - ikke kun smerter og tr\u00e6thed, men ogs\u00e5 potentielle effekter p\u00e5 fertiliteten. Inflammation, oxidativ stress og hormonelle forandringer kan alle skade s\u00e6dcellerne og p\u00e5virke den seksuelle sundhed. Der er dog gode nyheder: De fleste moderne behandlinger, is\u00e6r biologiske l\u00e6gemidler, ser ud til at v\u00e6re sikre for den mandlige reproduktive funktion.<\/p>\n<p><strong>M\u00e6nd, der lever med autoimmune sygdomme, kan bruge <a href=\"https:\/\/shop.exseedhealth.com\/collections\/male-fertility-test-kits\" target=\"_blank\" rel=\"noopener noreferrer\">S\u00e6dtests\u00e6t til hjemmebrug<\/a> til at spore fertilitetssundhed<\/strong> - herunder antallet af s\u00e6dceller, deres form og bev\u00e6gelighed. Test f\u00f8r eller under behandlingen hj\u00e6lper m\u00e6nd med at tr\u00e6ffe sikre beslutninger og arbejde t\u00e6ttere sammen med deres l\u00e6ger.<\/p>\n<p>Ved at h\u00e5ndtere sygdomsaktivitet tidligt og overv\u00e5ge fertiliteten regelm\u00e6ssigt kan m\u00e6nd beskytte deres reproduktive sundhed og planl\u00e6gge fremtidigt for\u00e6ldreskab med tillid.<\/p>","protected":false},"excerpt":{"rendered":"<p>Autoimmune diseases affect millions of people around the world, and some of them appear more often or more severely in men. These conditions usually cause inflammation and organ problems, but they also affect fertility \u2014 a side effect that\u2019s often overlooked. Below, we explore five autoimmune diseases that are more common in men and explain [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":150025,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"content-type":"","footnotes":""},"categories":[200,198],"tags":[],"class_list":["post-150021","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-lifestyle-environmental","category-mens-fertility"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v28.2 (Yoast SEO v28.7) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>How Autoimmune Diseases Affect Male Fertility<\/title>\n<meta name=\"description\" content=\"Discover how autoimmune diseases impact male fertility, plus how at-home sperm testing can help men monitor reproductive health.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.exseedhealth.com\/da\/autoimmune-diseases-in-men-how-they-impact-male-fertility\/\" \/>\n<meta property=\"og:locale\" content=\"da_DK\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"How Autoimmune Diseases Affect Male Fertility\" \/>\n<meta property=\"og:description\" content=\"Discover how autoimmune diseases impact male fertility, plus how at-home sperm testing can help men monitor reproductive health.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.exseedhealth.com\/da\/autoimmune-diseases-in-men-how-they-impact-male-fertility\/\" \/>\n<meta property=\"og:site_name\" content=\"ExSeed Health\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/ExSeedHealth\" \/>\n<meta property=\"article:published_time\" content=\"2025-07-31T14:42:03+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2025-11-12T14:08:30+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.exseedhealth.com\/wp-content\/uploads\/2025\/07\/Visualizing-the-Impact-of-Autoimmune-Disease-1024x576.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1024\" \/>\n\t<meta property=\"og:image:height\" content=\"576\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"Emil Andersen, PhD\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@ExSeed_Health\" \/>\n<meta name=\"twitter:site\" content=\"@ExSeed_Health\" \/>\n<meta name=\"twitter:label1\" content=\"Skrevet af\" \/>\n\t<meta name=\"twitter:data1\" content=\"Emil Andersen, PhD\" \/>\n\t<meta name=\"twitter:label2\" content=\"Estimeret l\u00e6setid\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutter\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.exseedhealth.com\\\/autoimmune-diseases-in-men-how-they-impact-male-fertility\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.exseedhealth.com\\\/autoimmune-diseases-in-men-how-they-impact-male-fertility\\\/\"},\"author\":{\"name\":\"Emil Andersen, PhD\",\"@id\":\"https:\\\/\\\/www.exseedhealth.com\\\/#\\\/schema\\\/person\\\/5d08eb43d90734a01dcf3cb77ce5e109\"},\"headline\":\"Autoimmune Diseases in Men: How They Impact Male Fertility\",\"datePublished\":\"2025-07-31T14:42:03+00:00\",\"dateModified\":\"2025-11-12T14:08:30+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.exseedhealth.com\\\/autoimmune-diseases-in-men-how-they-impact-male-fertility\\\/\"},\"wordCount\":690,\"publisher\":{\"@id\":\"https:\\\/\\\/www.exseedhealth.com\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/www.exseedhealth.com\\\/autoimmune-diseases-in-men-how-they-impact-male-fertility\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.exseedhealth.com\\\/wp-content\\\/uploads\\\/2025\\\/07\\\/Visualizing-the-Impact-of-Autoimmune-Disease.png\",\"articleSection\":[\"Lifestyle &amp; 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